Menstrual bleeding patterns following levonorgestrel emergency contraception.
نویسندگان
چکیده
PURPOSE Multiple trials by the World Health Organization have established levonorgestrel as the gold standard in hormonal emergency contraception (EC). However, changes in menstrual patterns following EC have been observed; thus, we undertook this prospective study to identify and determine the characteristics of these changes. MATERIALS Women requesting EC at either any of two hospitals --1 family planning unit and 12 pharmacies in Yaoundé, Cameroon were enrolled if they had a history of regular menstrual cycles over the previous 3 months and if they agreed to follow-up until the end of the subsequent menstrual cycle. Pretreatment menstrual patterns were compared with those of the EC treatment cycle and the cycle after EC. RESULTS In a set of 232 participants (mean age, 25 years), we observed 34 (14.7%) cases of incident intermenstrual bleeding and statistically significant changes in menstrual cycle length, menstrual period length and menstrual appearance compared to baseline patterns that differed according to whether EC was taken well before, close to or well after the expected ovulation for that cycle. The majority of these changes disappeared in the following cycle. CONCLUSION Levonorgestrel EC is associated with significant but transient changes in menstrual patterns in a significant proportion of users.
منابع مشابه
ACOG Recommendations on Emergency Contraception.
Emergency contraception is used to prevent pregnancy after unprotected or inadequately protected sexual intercourse. Common indications include contraceptive failure (e.g., condom breakage, missed doses of oral contraceptives) and failure to use any form of contraception. Although the first emergency contraceptive was approved by the U.S. Food and Drug Administration more than a decade ago, man...
متن کاملTolerability of levonorgestrel emergency contraception in adolescents.
OBJECTIVE We evaluated the tolerability of emergency contraception in adolescents. Study design In this descriptive study, 1 0.75 mg levonorgestrel tablet was administered to 52 females aged 13-16 with instructions to take the second tablet 12 hours later (unprotected intercourse was not an entry requirement). Participants kept diaries of side effects and menstrual patterns. We assessed correct...
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BACKGROUND Unintended pregnancy is a complex phenomenon which raise to take an emergency decision. Low contraceptive prevalence and high user failure rates are the leading causes of this unexpected situation. High user failure rates suggest the vital role of emergency contraception to prevent unplanned pregnancy. Levonorgestrel - a commonly used progestin for emergency contraception. However, l...
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متن کامل
Progesterone receptor modulator for emergency contraception: a randomized controlled trial.
OBJECTIVE Compare the efficacy and adverse effects of CDB-2914, a new progesterone receptor modulator, to levonorgestrel for emergency contraception. METHODS We performed a randomized, double-blinded noninferiority trial, enrolling healthy women seeking emergency contraception within 72 hours of unprotected intercourse. Participants were randomly assigned to receive a single dose of 50 mg of ...
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ورودعنوان ژورنال:
- Contraception
دوره 74 2 شماره
صفحات -
تاریخ انتشار 2006